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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK10
All Species:
14.41
Human Site:
S355
Identified Species:
26.41
UniProt:
Q15131
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15131
NP_001092003.2
360
41038
S355
P
A
T
S
E
G
Q
S
K
R
C
K
P
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546775
360
41038
S355
L
A
T
S
E
G
Q
S
K
R
C
K
P
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMM4
360
40942
S355
P
A
A
A
E
G
Q
S
K
R
C
R
P
_
_
Rat
Rattus norvegicus
Q4KM47
358
40615
S353
P
A
A
T
E
G
Q
S
K
R
C
R
P
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001103409
370
41951
T363
S
T
S
T
G
T
E
T
Q
A
K
R
A
K
P
Frog
Xenopus laevis
P23437
297
33852
Zebra Danio
Brachydanio rerio
NP_001017622
275
30997
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPC0
952
108820
K883
K
A
Q
A
S
S
P
K
P
P
S
G
G
S
Q
Honey Bee
Apis mellifera
XP_392973
410
46389
E381
A
P
P
K
E
T
R
E
P
E
T
T
V
T
D
Nematode Worm
Caenorhab. elegans
Q09437
719
83549
Q679
P
P
P
A
K
Q
K
Q
Q
E
N
R
I
S
H
Sea Urchin
Strong. purpuratus
XP_783449
397
44907
P375
N
T
R
P
E
H
R
P
A
M
Y
G
K
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
Q357
K
K
R
Q
Q
Q
R
Q
N
E
E
A
A
K
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
L360
F
Q
D
R
K
A
A
L
P
P
A
P
K
G
G
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93
N.A.
96.9
90.5
N.A.
N.A.
82.9
36.9
60.8
N.A.
21.3
63.9
25.8
63.7
Protein Similarity:
100
N.A.
N.A.
96.9
N.A.
98.8
93.6
N.A.
N.A.
89.7
53.6
69.1
N.A.
27.8
73.6
36.4
75.8
P-Site Identity:
100
N.A.
N.A.
92.3
N.A.
76.9
76.9
N.A.
N.A.
0
0
0
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
92.3
N.A.
92.3
92.3
N.A.
N.A.
40
0
0
N.A.
13.3
13.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.4
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
45.5
N.A.
43.6
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
16
24
0
8
8
0
8
8
8
8
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
47
0
8
8
0
24
8
0
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
31
0
0
0
0
0
16
8
8
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
16
8
0
8
16
0
8
8
31
0
8
16
16
16
0
% K
% Leu:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% N
% Pro:
31
16
16
8
0
0
8
8
24
16
0
8
31
0
8
% P
% Gln:
0
8
8
8
8
16
31
16
16
0
0
0
0
0
8
% Q
% Arg:
0
0
16
8
0
0
24
0
0
31
0
31
0
0
8
% R
% Ser:
8
0
8
16
8
8
0
31
0
0
8
0
0
16
0
% S
% Thr:
0
16
16
16
0
16
0
8
0
0
8
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
31
% _